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praja2 regulates KSR1 stability and mitogenic signaling
The kinase suppressor of Ras 1 (KSR1) has a fundamental role in mitogenic signaling by scaffolding components of the Ras/MAP kinase pathway. In response to Ras activation, KSR1 assembles a tripartite kinase complex that optimally transfers signals generated at the cell membrane to activate ERK. We d...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4917648/ https://ncbi.nlm.nih.gov/pubmed/27195677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.109 |
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