The TBC1D31/praja2 complex controls primary ciliogenesis through PKA‐directed OFD1 ubiquitylation

The primary cilium is a microtubule‐based sensory organelle that dynamically links signalling pathways to cell differentiation, growth, and development. Genetic defects of primary cilia are responsible for genetic disorders known as ciliopathies. Orofacial digital type I syndrome (OFDI) is an X‐link...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Senatore, Emanuela, Chiuso, Francesco, Rinaldi, Laura, Intartaglia, Daniela, Delle Donne, Rossella, Pedone, Emilia, Catalanotti, Bruno, Pirone, Luciano, Fiorillo, Bianca, Moraca, Federica, Giamundo, Giuliana, Scala, Giovanni, Raffeiner, Andrea, Torres‐Quesada, Omar, Stefan, Eduard, Kwiatkowski, Marcel, van Pijkeren, Alienke, Morleo, Manuela, Franco, Brunella, Garbi, Corrado, Conte, Ivan, Feliciello, Antonio
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126939/
https://ncbi.nlm.nih.gov/pubmed/33934390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106503
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