The TBC1D31/praja2 complex controls primary ciliogenesis through PKA‐directed OFD1 ubiquitylation

The primary cilium is a microtubule‐based sensory organelle that dynamically links signalling pathways to cell differentiation, growth, and development. Genetic defects of primary cilia are responsible for genetic disorders known as ciliopathies. Orofacial digital type I syndrome (OFDI) is an X‐link...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Senatore, Emanuela, Chiuso, Francesco, Rinaldi, Laura, Intartaglia, Daniela, Delle Donne, Rossella, Pedone, Emilia, Catalanotti, Bruno, Pirone, Luciano, Fiorillo, Bianca, Moraca, Federica, Giamundo, Giuliana, Scala, Giovanni, Raffeiner, Andrea, Torres‐Quesada, Omar, Stefan, Eduard, Kwiatkowski, Marcel, van Pijkeren, Alienke, Morleo, Manuela, Franco, Brunella, Garbi, Corrado, Conte, Ivan, Feliciello, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126939/
https://ncbi.nlm.nih.gov/pubmed/33934390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106503
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