Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation

Background: Rats subjected to bile duct ligation (BDL) exhibit increased systemic oxidative stress and brain dysfunction characteristic of hepatic encephalopathy (HE), including fatigue, neurotransmitter alterations, cognitive and motor impairment, and brain inflammation. The levels of tumor necrosi...

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Foilsithe in:Front Cell Neurosci
Main Authors: Sheen, Jiunn-Ming, Chen, Yu-Chieh, Hsu, Mei-Hsin, Tain, You-Lin, Yu, Hong-Ren, Huang, Li-Tung
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2016
Ábhair:
Neuroscience
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917524/
https://ncbi.nlm.nih.gov/pubmed/27445694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00167
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