Combined Intraperitoneal and Intrathecal Etanercept Reduce Increased Brain Tumor Necrosis Factor-Alpha and Asymmetric Dimethylarginine Levels and Rescues Spatial Deficits in Young Rats after Bile Duct Ligation

Background: Rats subjected to bile duct ligation (BDL) exhibit increased systemic oxidative stress and brain dysfunction characteristic of hepatic encephalopathy (HE), including fatigue, neurotransmitter alterations, cognitive and motor impairment, and brain inflammation. The levels of tumor necrosi...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Sheen, Jiunn-Ming, Chen, Yu-Chieh, Hsu, Mei-Hsin, Tain, You-Lin, Yu, Hong-Ren, Huang, Li-Tung
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917524/
https://ncbi.nlm.nih.gov/pubmed/27445694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00167
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