Increased Circulatory Asymmetric Dimethylarginine and Multiple Organ Failure: Bile Duct Ligation in Rat as a Model

Bile duct ligation (BDL)-treated rats exhibit cholestasis, increased systemic oxidative stress, and liver fibrosis, which ultimately lead to liver cirrhosis. Asymmetric dimethylarginine (ADMA) is a competitive inhibitor of nitric oxide synthase that can decrease the synthesis of nitric oxide. BDL ra...

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Hlavní autoři: Sheen, Jiunn-Ming, Chen, Yu-Chieh, Tain, You-Lin, Huang, Li-Tung
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Diversity Preservation International (MDPI) 2014
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975379/
https://ncbi.nlm.nih.gov/pubmed/24603538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15033989
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