Store-operated Ca(2+) entry in follicular T cells controls humoral immune responses and autoimmunity

T follicular helper (Tfh) cells promote affinity maturation of B cells in germinal centers (GCs), whereas T follicular regulatory (Tfr) cells limit the GC reaction. Store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels mediated by STIM and ORAI proteins is a fund...

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Gepubliceerd in:Immunity
Hoofdauteurs: Vaeth, Martin, Eckstein, Miriam, Shaw, Patrick, Kozhaya, Lina, Yang, Jun, Berberich-Siebelt, Friederike, Clancy, Robert, Unutmaz, Derya, Feske, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917422/
https://ncbi.nlm.nih.gov/pubmed/27261277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.04.013
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