Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in “driver-negative” lung adenocarcinomas

PURPOSE: Broad, hybrid capture-based next-generation sequencing (NGS), as a clinical test, uses less tissue to identify more clinically relevant genomic alterations compared to profiling with multiple non-NGS tests. We set out to determine the frequency of such genomic alterations via this approach...

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Udgivet i:Clin Cancer Res
Main Authors: Drilon, Alexander, Wang, Lu, Arcila, Maria E., Balasubramanian, Sohail, Greenbowe, Joel R., Ross, Jeffrey S., Stephens, Phil, Lipson, Doron, Miller, Vincent A., Kris, Mark G., Ladanyi, Marc, Rizvi, Naiyer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4917003/
https://ncbi.nlm.nih.gov/pubmed/25567908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2683
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