Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

PURPOSE: The majority of broad-panel tumor genomic profiling has used a gene-centric approach, although much of that data is unused in clinical decision-making. We hypothesized that a pathway-centric approach using next-generation sequencing, combined with conventional clinicopathologic features, ma...

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Détails bibliographiques
Publié dans:Clin Cancer Res
Auteurs principaux: Zhou, Jian, Sanchez-Vega, Francisco, Caso, Raul, Tan, Kay See, Brandt, Whitney S., Jones, Gregory D., Yan, Shi, Adusumilli, Prasad S., Bott, Matthew J., Huang, James, Isbell, James M., Sihag, Smita, Molena, Daniela, Rusch, Valerie W., Chatila, Walid K., Rekhtman, Natasha, Yang, Fan, Ladanyi, Marc, Solit, David B., Berger, Michael F., Schultz, Nikolaus, Jones, David R.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911636/
https://ncbi.nlm.nih.gov/pubmed/31455678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1651
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