Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

PURPOSE: The majority of broad-panel tumor genomic profiling has used a gene-centric approach, although much of that data is unused in clinical decision-making. We hypothesized that a pathway-centric approach using next-generation sequencing, combined with conventional clinicopathologic features, ma...

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Udgivet i:Clin Cancer Res
Main Authors: Zhou, Jian, Sanchez-Vega, Francisco, Caso, Raul, Tan, Kay See, Brandt, Whitney S., Jones, Gregory D., Yan, Shi, Adusumilli, Prasad S., Bott, Matthew J., Huang, James, Isbell, James M., Sihag, Smita, Molena, Daniela, Rusch, Valerie W., Chatila, Walid K., Rekhtman, Natasha, Yang, Fan, Ladanyi, Marc, Solit, David B., Berger, Michael F., Schultz, Nikolaus, Jones, David R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911636/
https://ncbi.nlm.nih.gov/pubmed/31455678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1651
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