Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

PURPOSE: The majority of broad-panel tumor genomic profiling has used a gene-centric approach, although much of that data is unused in clinical decision-making. We hypothesized that a pathway-centric approach using next-generation sequencing, combined with conventional clinicopathologic features, ma...

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Publicado en:Clin Cancer Res
Autores principales: Zhou, Jian, Sanchez-Vega, Francisco, Caso, Raul, Tan, Kay See, Brandt, Whitney S., Jones, Gregory D., Yan, Shi, Adusumilli, Prasad S., Bott, Matthew J., Huang, James, Isbell, James M., Sihag, Smita, Molena, Daniela, Rusch, Valerie W., Chatila, Walid K., Rekhtman, Natasha, Yang, Fan, Ladanyi, Marc, Solit, David B., Berger, Michael F., Schultz, Nikolaus, Jones, David R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911636/
https://ncbi.nlm.nih.gov/pubmed/31455678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1651
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