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Catalytic Promiscuity of the Radical S-adenosyl-L-methionine Enzyme NosL

Catalytic promiscuity plays a key role in enzyme evolution and the acquisition of novel biological functions. Because of the high reactivity of radical species, in our view enzymes involving radical-mediated mechanisms could intrinsically be more prone to catalytic promiscuity. This mini-review summ...

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Bibliographic Details
Published in:Front Chem
Main Authors: Ding, Wei, Ji, Xinjian, Li, Yongzhen, Zhang, Qi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916742/
https://ncbi.nlm.nih.gov/pubmed/27446906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00027
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