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Mechanism of Radical Initiation in the Radical S-Adenosyl-L-methionine Superfamily

The seeds for recognition of the vast superfamily of radical S-adenosyl-L-methionine (SAM) enzymes were sown in the 1960s, when Joachim Knappe found that the dissimilation of pyruvate was dependent on SAM and Fe(II), and Barker and co-workers made similar observations for lysine 2,3-aminomutase. The...

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Detalhes bibliográficos
Publicado no:Acc Chem Res
Main Authors: Broderick, William E., Hoffman, Brian M., Broderick, Joan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6324848/
https://ncbi.nlm.nih.gov/pubmed/30346729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.8b00356
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