Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1

The purpose of present study was to investigate the effect of dioscin on activity of adriamycin (ADR) in ADR-sensitive (MCF-7) and ADR-resistant (MCF-7/ADR) human breast cancer cells and to clarify the molecular mechanisms involved. Antiproliferation effect of ADR was enhanced by dioscin in MCF-7 an...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Changyuan, Huo, Xiaokui, Wang, Lijuan, Meng, Qiang, Liu, Zhihao, Liu, Qi, Sun, Huijun, Sun, Pengyuan, Peng, Jinyong, Liu, Kexin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916600/
https://ncbi.nlm.nih.gov/pubmed/27329817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28403
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