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Silencing of ETS1 reverses adriamycin resistance in MCF-7/ADR cells via downregulation of MDR1

BACKGROUND: Clinical resistance to chemotherapeutic agents is one of the major hindrances in the treatment of human cancers. Erythroblastosis virus E26 oncogene homolog 1 (ETS1) is involved in the drug resistance of various cancer cells, and is overexpressed in drug-resistant human breast cancer cel...

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Detalhes bibliográficos
Main Authors: Wei, Jinrong, Zhou, Yong, Jiang, Guo-Qin, Xiao, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995875/
https://ncbi.nlm.nih.gov/pubmed/24602286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-22
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