A Randomized, Double-Blind, Placebo-Controlled Phase II Trial Investigating the Safety and Immunogenicity of Modified Vaccinia Ankara Smallpox Vaccine (MVA-BN®) in 56-80-Year-Old Subjects

BACKGROUND: Modified Vaccinia Ankara MVA-BN(®) is a live, highly attenuated, viral vaccine under advanced development as a non-replicating smallpox vaccine. In this Phase II trial, the safety and immunogenicity of Modified Vaccinia Ankara MVA-BN(®) (MVA) was assessed in a 56–80 years old population....

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Bibliographic Details
Published in:PLoS One
Main Authors: Greenberg, Richard N., Hay, Christine M., Stapleton, Jack T., Marbury, Thomas C., Wagner, Eva, Kreitmeir, Eva, Röesch, Siegfried, von Krempelhuber, Alfred, Young, Philip, Nichols, Richard, Meyer, Thomas P., Schmidt, Darja, Weigl, Josef, Virgin, Garth, Arndtz-Wiedemann, Nathaly, Chaplin, Paul
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915701/
https://ncbi.nlm.nih.gov/pubmed/27327616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157335
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