Blockade of the GLT-1 Transporter in the Central Nucleus of the Amygdala Induces both Anxiety and Depressive-Like Symptoms

Depression has been associated with abnormalities in glutamatergic neurotransmission and decreased astrocyte number in limbic areas. We previously demonstrated that global and prefrontal cortical blockade of the astrocytic glutamate transporter (GLT-1) induces anhedonia and c-Fos expression in areas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuropsychopharmacology
Egile Nagusiak: John, Catherine S, Sypek, Elizabeth I, Carlezon, William A, Cohen, Bruce M, Öngür, Dost, Bechtholt, Anita J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915252/
https://ncbi.nlm.nih.gov/pubmed/25586634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.16
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