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Blockade of protein phosphatase 2B activity in the amygdala increases anxiety- and depression-like behaviors in mice
BACKGROUND: Organ transplant patients receive chronic administration of the calcineurin inhibitor Cyclosporin-A (CsA) and demonstrate increased incidence of mood disorders. Significant calcineurin expression can be observed using immunohistochemistry in the amygdala, a brain area important for behav...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787791/ https://ncbi.nlm.nih.gov/pubmed/19716552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.07.004 |
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