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Calcineurin down-regulation in the amygdala is sufficient to induce anxiety-like and depression-like behaviors in C57BL/6J male mice
BACKGROUND: The calcium-dependent phosphatase calcineurin is highly expressed in the amygdala, a brain area important for behaviors related to mood disorders and anxiety. Organ transplant patients are administered the calcineurin inhibitor Cyclosporin-A (CsA) chronically and demonstrate an increased...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4037359/ https://ncbi.nlm.nih.gov/pubmed/24742621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.03.009 |
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