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Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage

The GTPase RhoA promotes contractile ring assembly and furrow ingression during cytokinesis. Although many factors that regulate RhoA during cytokinesis have been characterized, the spatiotemporal regulatory logic remains undefined. We have developed an optogenetic probe to gain tight spatial and te...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Wagner, Elizabeth, Glotzer, Michael
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915195/
https://ncbi.nlm.nih.gov/pubmed/27298323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603025
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