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Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage

The GTPase RhoA promotes contractile ring assembly and furrow ingression during cytokinesis. Although many factors that regulate RhoA during cytokinesis have been characterized, the spatiotemporal regulatory logic remains undefined. We have developed an optogenetic probe to gain tight spatial and te...

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Pubblicato in:J Cell Biol
Autori principali: Wagner, Elizabeth, Glotzer, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915195/
https://ncbi.nlm.nih.gov/pubmed/27298323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603025
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