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Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage

The GTPase RhoA promotes contractile ring assembly and furrow ingression during cytokinesis. Although many factors that regulate RhoA during cytokinesis have been characterized, the spatiotemporal regulatory logic remains undefined. We have developed an optogenetic probe to gain tight spatial and te...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Wagner, Elizabeth, Glotzer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915195/
https://ncbi.nlm.nih.gov/pubmed/27298323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603025
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