Yüklüyor......
Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3
Targeting mTORC1 is a highly promising strategy in cancer therapy. Suppression of mTORC1 activity leads to rapid dephosphorylation of eIF4E-binding proteins (4E-BP1–3) and subsequent inhibition of mRNA translation. However, how the different 4E-BPs affect translation during prolonged use of mTOR inh...
Kaydedildi:
| Yayımlandı: | Nat Commun |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4915159/ https://ncbi.nlm.nih.gov/pubmed/27319316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11776 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|