ロード中...
Translation control during prolonged mTORC1 inhibition mediated by 4E-BP3
Targeting mTORC1 is a highly promising strategy in cancer therapy. Suppression of mTORC1 activity leads to rapid dephosphorylation of eIF4E-binding proteins (4E-BP1–3) and subsequent inhibition of mRNA translation. However, how the different 4E-BPs affect translation during prolonged use of mTOR inh...
保存先:
| 出版年: | Nat Commun |
|---|---|
| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4915159/ https://ncbi.nlm.nih.gov/pubmed/27319316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11776 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|