Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling

Cellular signaling processes can exhibit pronounced cell-to-cell variability in genetically identical cells. This affects how individual cells respond differentially to the same environmental stimulus. However, the origins of cell-to-cell variability in cellular signaling systems remain poorly under...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Filippi, Sarah, Barnes, Chris P., Kirk, Paul D.W., Kudo, Takamasa, Kunida, Katsuyuki, McMahon, Siobhan S., Tsuchiya, Takaho, Wada, Takumi, Kuroda, Shinya, Stumpf, Michael P.H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914773/
https://ncbi.nlm.nih.gov/pubmed/27264188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.024
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