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Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB

Efflux pumps of the resistance nodulation cell division (RND) transporter family, such as AcrB of Escherichia coli, play an important role in the development of multidrug resistance, but the molecular basis for their substrate promiscuity is not yet completely understood. From a collection of highly...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Schuster, Sabine, Vavra, Martina, Kern, Winfried V.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914648/
https://ncbi.nlm.nih.gov/pubmed/27161641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00314-16
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