Regression/Eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide

Malignant gliomas have poor prognosis and urgently require new therapies. Activating Transcription Factor 5 (ATF5) is highly expressed in gliomas, and interference with its expression/function precipitates targeted glioma cell apoptosis in vitro and in vivo. We designed a novel deliverable truncated...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cates, Charles C., Arias, Angelo D., Wong, Lynn S. Nakayama, Lamé, Michael W., Sidorov, Maxim, Cayanan, Geraldine, Rowland, Douglas J., Fung, Jennifer, Karpel-Massler, Georg, Siegelin, Markus D., Greene, Lloyd A., Angelastro, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914317/
https://ncbi.nlm.nih.gov/pubmed/26863637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7212
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