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Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD

The basic leucine zipper transcription factor ATF5 is over-expressed in many tumor types and interference with its expression or function inhibits cancer cell survival. As a potential therapeutic approach to exploit these findings, we created dominant-negative (DN) ATF5 forms lacking DNA-binding abi...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Sun, Xiaotian, Jefferson, Parvaneh, Zhou, Qing, Angelastro, James M., Greene, Lloyd A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561279/
https://ncbi.nlm.nih.gov/pubmed/31676720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0631
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