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Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD
The basic leucine zipper transcription factor ATF5 is over-expressed in many tumor types and interference with its expression or function inhibits cancer cell survival. As a potential therapeutic approach to exploit these findings, we created dominant-negative (DN) ATF5 forms lacking DNA-binding abi...
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| Publicado en: | Mol Cancer Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7561279/ https://ncbi.nlm.nih.gov/pubmed/31676720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0631 |
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