Non‐glycosidic compounds can stimulate both human and mouse iNKT cells

Invariant natural killer T (iNKT) cells recognize CD1d/glycolipid complexes and upon activation with synthetic agonists display immunostimulatory properties. We have previously described that the non‐glycosidic CD1d‐binding lipid, threitolceramide (ThrCer) activates murine and human iNKT cells. Here...

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Detalles Bibliográficos
Publicado en:Eur J Immunol
Autores principales: Jukes, John‐Paul, Gileadi, Uzi, Ghadbane, Hemza, Yu, Ting‐Fong, Shepherd, Dawn, Cox, Liam R., Besra, Gurdyal S., Cerundolo, Vincenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Immunomodulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913735/
https://ncbi.nlm.nih.gov/pubmed/26873393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546114
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