Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction

Invariant natural killer T (iNKT) cells are a specialized T-cell subset that recognizes lipids as antigens, contributing to immune responses in diverse disease processes. Experimental data suggests that iNKT cells can recognize both microbial and endogenous lipid antigens. Several candidate endogeno...

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Main Authors: Brennan, Patrick J., Tatituri, Raju V. V., Heiss, Christian, Watts, Gerald F. M., Hsu, Fong-Fu, Veerapen, Natacha, Cox, Liam R., Azadi, Parastoo, Besra, Gurdyal S., Brenner, Michael B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169973/
https://ncbi.nlm.nih.gov/pubmed/25197085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415357111
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