Distinct requirements for CD1d intracellular transport for development of Vα14 iNKT cells

The positive selection of Vα14 invariant (i)NKT cells in mice requires CD1dmediated antigen presentation by CD4(+) CD8(+) thymocytes. Maturation of newly selected iNKT cells continues in the periphery also involves CD1d expression. CD1d molecules acquire antigens for presentation in endosomal compar...

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Bibliographic Details
Main Authors: Sillé, Fenna C. M., Boxem, Mike, Sprengers, Dave, Veerapen, Natacha, Besra, Gurdyal, Boes, Marianne
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839504/
https://ncbi.nlm.nih.gov/pubmed/19587020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901354
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