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Critical role for Invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells
The development and maturation of Vα14 invariant (i)NKT cells in mice requires CD1d-mediated lipid antigen presentation in the thymus and the periphery. Cortical thymocytes mediate positive selection, while professional APCs are involved in thymic negative selection and in terminal maturation of iNK...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146573/ https://ncbi.nlm.nih.gov/pubmed/21565221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2011.04.012 |
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