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Critical role for Invariant chain in CD1d-mediated selection and maturation of Vα14-invariant NKT cells

The development and maturation of Vα14 invariant (i)NKT cells in mice requires CD1d-mediated lipid antigen presentation in the thymus and the periphery. Cortical thymocytes mediate positive selection, while professional APCs are involved in thymic negative selection and in terminal maturation of iNK...

詳細記述

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書誌詳細
主要な著者: Sillé, Fenna C. M., Martin, Constance, Jayaraman, Pushpa, Rothchild, Alissa, Besra, Gurdyal S., Behar, Samuel M., Boes, Marianne
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146573/
https://ncbi.nlm.nih.gov/pubmed/21565221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2011.04.012
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