Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition

Invariant natural killer T (iNKT) cells recognize self lipid antigens presented by CD1d molecules. The nature of the self-antigens involved in the development and maturation of iNKT cells is poorly defined. Lysophospholipids are self-antigens presented by CD1d that are generated through the action o...

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Autores principales: Paduraru, Crina, Bezbradica, Jelena S., Kunte, Amit, Kelly, Robert, Shayman, James A., Veerapen, Natacha, Cox, Liam R., Besra, Gurdyal S., Cresswell, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612615/
https://ncbi.nlm.nih.gov/pubmed/23493550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302923110
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