Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue

Activation of inflammation in white adipose tissue (WAT), includes infiltration/expansion of WAT macrophages, contributes pathogenesis of obesity, insulin resistance, and metabolic syndrome. The inflammasome comprises an intracellular sensor (NLR), caspase-1 and the adaptor ASC. Inflammasome activat...

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發表在:Sci Rep
Main Authors: Ahmad, Faiyaz, Chung, Youn Wook, Tang, Yan, Hockman, Steven C., Liu, Shiwei, Khan, Yusuf, Huo, Kevin, Billings, Eric, Amar, Marcelo J., Remaley, Alan T., Manganiello, Vincent C.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913246/
https://ncbi.nlm.nih.gov/pubmed/27321128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28056
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