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Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue
Activation of inflammation in white adipose tissue (WAT), includes infiltration/expansion of WAT macrophages, contributes pathogenesis of obesity, insulin resistance, and metabolic syndrome. The inflammasome comprises an intracellular sensor (NLR), caspase-1 and the adaptor ASC. Inflammasome activat...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4913246/ https://ncbi.nlm.nih.gov/pubmed/27321128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28056 |
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