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Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue
Activation of inflammation in white adipose tissue (WAT), includes infiltration/expansion of WAT macrophages, contributes pathogenesis of obesity, insulin resistance, and metabolic syndrome. The inflammasome comprises an intracellular sensor (NLR), caspase-1 and the adaptor ASC. Inflammasome activat...
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| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4913246/ https://ncbi.nlm.nih.gov/pubmed/27321128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28056 |
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