Circadian Amplitude Regulation via FBXW7-targeted REV-ERBα Degradation

Defects in circadian rhythm influence physiology and behavior with implications for the treatment of sleep disorders, metabolic disease and cancer. Although core regulatory components of clock rhythmicity have been defined, insight into the mechanisms underpinning amplitude is limited. We show here...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Zhao, Xuan, Hirota, Tsuyoshi, Han, Xuemei, Cho, Han, Chong, Ling-Wa, Lamia, Katja, Liu, Sihao, Atkins, Annette R., Banayo, Ester, Liddle, Christopher, Yu, Ruth T., Yates, John R., Kay, Steve A., Downes, Michael, Evans, Ronald M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912445/
https://ncbi.nlm.nih.gov/pubmed/27238018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.012
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