Circadian Amplitude Regulation via FBXW7-targeted REV-ERBα Degradation

Defects in circadian rhythm influence physiology and behavior with implications for the treatment of sleep disorders, metabolic disease and cancer. Although core regulatory components of clock rhythmicity have been defined, insight into the mechanisms underpinning amplitude is limited. We show here...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Zhao, Xuan, Hirota, Tsuyoshi, Han, Xuemei, Cho, Han, Chong, Ling-Wa, Lamia, Katja, Liu, Sihao, Atkins, Annette R., Banayo, Ester, Liddle, Christopher, Yu, Ruth T., Yates, John R., Kay, Steve A., Downes, Michael, Evans, Ronald M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912445/
https://ncbi.nlm.nih.gov/pubmed/27238018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.012
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