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Activation of Wnt/β-catenin Signaling by Hydrogen Peroxide Transcriptionally Inhibits Na(V)1.5 Expression
Oxidants and canonical Wnt/β-catenin signaling have been shown to decrease cardiac Na(+) channel activity by suppressing Na(V)1.5 expression. Our aims are to determine if hydrogen peroxide (H(2)O(2)), one oxidant of reactive oxygen species (ROS), activates Wnt/β-catenin signaling and promotes β-cate...
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| I publikationen: | Free Radic Biol Med |
|---|---|
| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912406/ https://ncbi.nlm.nih.gov/pubmed/27068063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.04.003 |
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