Canonical Wnt/β-catenin signaling in epicardial fibrosis of failed pediatric heart allografts with diastolic dysfunction

BACKGROUND: Failed pediatric heart allografts with diastolic dysfunction exhibit severe epicardial fibrosis. The molecular mechanism underlying this process is poorly understood. Canonical Wnt/β-catenin signaling plays an important role in epithelial-mesenchymal transition and is implicated in fibro...

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Main Authors: Ye, Bo, Ge, Yao, Perens, Gregory, Hong, Longsheng, Xu, Haodong, Fishbein, Michael C., Li, Faqian
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427707/
https://ncbi.nlm.nih.gov/pubmed/22475572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2012.03.004
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