A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

Mutations in transcription factors (TFs) genes are frequently observed in tumors, often leading to aberrant transcriptional activity. Unfortunately, TFs are often considered undruggable due to the absence of targetable enzymatic activity. To address this problem, we developed CRAFTT, a Computational...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Gayvert, Kaitlyn, Dardenne, Etienne, Cheung, Cynthia, Boland, Mary Regina, Lorberbaum, Tal, Wanjala, Jackline, Chen, Yu, Rubin, Mark, Tatonetti, Nicholas P., Rickman, David, Elemento, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912004/
https://ncbi.nlm.nih.gov/pubmed/27264179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.037
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados