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Systems Biology Approaches for Identifying Adverse Drug Reactions and Elucidating Their Underlying Biological Mechanisms

Small molecules are indispensable to modern medical therapy. However, their use may lead to unintended, negative medical outcomes commonly referred to as adverse drug reactions (ADRs). These effects vary widely in mechanism, severity, and populations affected, making ADR prediction and identificatio...

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Veröffentlicht in:Wiley Interdiscip Rev Syst Biol Med
Hauptverfasser: Boland, Mary Regina, Jacunski, Alexandra, Lorberbaum, Tal, Romano, Joseph, Moskovitch, Robert, Tatonetti, Nicholas P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760887/
https://ncbi.nlm.nih.gov/pubmed/26559926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1323
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