Systems Biology Approaches for Identifying Adverse Drug Reactions and Elucidating Their Underlying Biological Mechanisms

Small molecules are indispensable to modern medical therapy. However, their use may lead to unintended, negative medical outcomes commonly referred to as adverse drug reactions (ADRs). These effects vary widely in mechanism, severity, and populations affected, making ADR prediction and identificatio...

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Bibliographic Details
Published in:Wiley Interdiscip Rev Syst Biol Med
Main Authors: Boland, Mary Regina, Jacunski, Alexandra, Lorberbaum, Tal, Romano, Joseph, Moskovitch, Robert, Tatonetti, Nicholas P.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760887/
https://ncbi.nlm.nih.gov/pubmed/26559926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1323
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