MYC is a crucial mediator of TGFβ-induced invasion in basal breast cancer

Basal subtype breast cancers have a particularly poor prognosis, with high invasiveness and resistance to most targeted therapies. TGFβ and MYC drive central features of basal breast cancer: TGFβ is an autocrine and paracrine signaling factor that drives cell invasion and metastasis, and MYC is a ce...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Cichon, Magdalena A., Moruzzi, Megan E., Shqau, Tiziana A., Miller, Erin, Mehner, Christine, Ethier, Stephen P., Copland, John A., Radisky, Evette S., Radisky, Derek C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911305/
https://ncbi.nlm.nih.gov/pubmed/27197167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-3465
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