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Side-chain-to-tail cyclization of ribosomally derived peptides promoted by aryl and alkyl amino-functionalized unnatural amino acids

A strategy for the production of side-chain-to-tail cyclic peptides from ribosomally derived polypeptide precursors is reported. Two genetically encodable unnatural amino acids, bearing either an aryl or alkyl amino group, were investigated for their efficiency toward promoting the formation of medi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Org Biomol Chem
Egile Nagusiak: Frost, John R., Wu, Zhijie, Lam, Yick Chong, Owens, Andrew E., Fasan, Rudi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909536/
https://ncbi.nlm.nih.gov/pubmed/27064594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ob00192k
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