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Synthesis of Macrocyclic Organo-Peptide Hybrids from Ribosomal Polypeptide Precursors via CuAAC-/hydrazide-mediated cyclization

Macrocyclic peptides have attracted increasing attention as a potential new source of chemical probes and therapeutics. In particular, their conformationally restricted structure combined with a high degree of functional and stereochemical complexity make them promising scaffolds for targeting biomo...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Smith, Jessica M., Fasan, Rudi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481324/
https://ncbi.nlm.nih.gov/pubmed/25616323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2020-4_2
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