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A mitosis-sensing caspase activation platform? New insights into the PIDDosome

In contrast to the apoptosome and death-inducing signaling complex, the PIDDosome remains an orphan caspase activation platform unassigned to a specific apoptotic pathway. We found that DNA damage-induced PIDDosome formation is blocked by the mitotic checkpoint factor BUBR1 (budding uninhibited by b...

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Publicat a:Mol Cell Oncol
Autors principals: Shah, Richa B., Thompson, Ruth, Sidi, Samuel
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909455/
https://ncbi.nlm.nih.gov/pubmed/27314076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1059921
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