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A mitosis-sensing caspase activation platform? New insights into the PIDDosome
In contrast to the apoptosome and death-inducing signaling complex, the PIDDosome remains an orphan caspase activation platform unassigned to a specific apoptotic pathway. We found that DNA damage-induced PIDDosome formation is blocked by the mitotic checkpoint factor BUBR1 (budding uninhibited by b...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909455/ https://ncbi.nlm.nih.gov/pubmed/27314076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1059921 |
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