The CDC20-APC/SOX2 signaling axis: An achilles' heel for glioblastoma

Glioblastoma stem-like cells (GSCs) play a critical role in glioblastoma progression and recurrence. We discuss recent results on the role of the mitotic ubiquitin ligase cell division cycle 20–anaphase-promoting complex (CDC20-APC) in the governance of cardinal GSC functions through a mechanism inv...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Gujar, Amit D., Yano, Hiroko, Kim, Albert H.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909416/
https://ncbi.nlm.nih.gov/pubmed/27314081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1075644
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