A CDC20-APC/SOX2 Signaling Axis Regulates Human Glioblastoma Stem-Like Cells

Glioblastoma harbors a dynamic subpopulation of glioblastoma stem-like cells (GSCs) that can propagate tumors in vivo and is resistant to standard chemoradiation. Identification of the cell-intrinsic mechanisms governing this clinically important cell state may lead to the discovery of novel therape...

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Vydáno v:Cell Rep
Hlavní autoři: Mao, Diane D, Gujar, Amit D, Mahlokozera, Tatenda, Chen, Ishita, Pan, Yanchun, Luo, Jingqin, Brost, Taylor, Thompson, Elizabeth A, Turski, Alice, Leuthardt, Eric C, Dunn, Gavin P, Chicoine, Michael R, Rich, Keith M, Dowling, Joshua L, Zipfel, Gregory J, Dacey, Ralph G, Achilefu, Samuel, Tran, David D, Yano, Hiroko, Kim, Albert H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481182/
https://ncbi.nlm.nih.gov/pubmed/26074073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.027
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